Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease

Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease

Trypanosoma cruzi strains from distinct geographic areas show differences in drug resistance and association between parasites genetic and treatment response has been observed. Considering that benznidazole (BZ) can reduce the parasite burden and tissues damage, even in not cured animals and individ...

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Bibliographic Details
Main Authors: Jaquelline Carla Valamiel de Oliveira-Silva, Girley Francisco Machado-de-Assis, Maykon Tavares Oliveira, Nívia Carolina Noguieira Paiva, Márcio Sobreira Silva Araújo, Cláudia Martins Carneiro, Olindo Assis Martins-Filho, Helen Rodrigues Martins, Marta de Lana
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2015-02-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Trypanosoma cruzi II
benznidazole response
acute and chronic phases
murine model
Jequitinhonha Valley
MG
Brazil
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000100086&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000100086&lng=en&tlng=en

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