Contribution of IL-17 in Steroid Hyporesponsiveness in Obese Asthmatics Through Dysregulation of Glucocorticoid Receptors α and β

Contribution of IL-17 in Steroid Hyporesponsiveness in Obese Asthmatics Through Dysregulation of Glucocorticoid Receptors α and β

Obesity is on the rise worldwide and is one of the most common comorbidities of asthma. The chronic inflammation seen in obesity is believed to contribute to this process. Asthma and obesity are associated with a poorer prognosis, more frequent exacerbations, and poor asthma control to standard cont...

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Bibliographic Details
Main Authors: Saba Al Heialy, Mellissa Gaudet, Rakhee K. Ramakrishnan, Andrea Mogas, Laila Salameh, Bassam Mahboub, Qutayba Hamid
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
asthma
obesity
IL-17
steroid hyporesponsiveness
glucocorticoid receptors
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01724/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01724/full

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