QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors

QSAR Studies on Andrographolide Derivatives as α-Glucosidase Inhibitors

Andrographolide derivatives were shown to inhibit α-glucosidase. To investigate the relationship between activities and structures of andrographolide derivatives, a training set was chosen from 25 andrographolide derivatives by the principal component analysis (PCA) method, and a quantitative struct...

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Bibliographic Details
Main Authors: Shaohui Cai, Jiaolin Bao, Guoji Li, Haibin Luo, Sichao Huang, Jun Xu, Yuqiang Wang
Format: Article
Language:English
Published: MDPI AG 2010-03-01
Series:International Journal of Molecular Sciences
Subjects:
andrographolide
QSAR
α-glucosidase
HQSAR
Online Access:http://www.mdpi.com/1422-0067/11/3/880/

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