Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma

<b>Objective:</b>Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC).<br/><b>Methods:</b>A total of 473 patients with LSCC i...

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Main Authors: Zhao-Qu Li, Lan Zou, Tian-Run Liu, An-Kui Yang
Format: Article
Language:English
Published: China Anti-Cancer Association 2015-12-01
Series:Cancer Biology & Medicine
Subjects:
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/893
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spelling doaj-1bf271e0da264dc0be7861c2885a6afc2020-11-25T02:03:26ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412015-12-0112439440010.7497/j.issn.2095-3941.2015.00432015000043Prognostic value of body mass index before treatment for laryngeal squamous cell carcinomaZhao-Qu Li0Lan Zou1Tian-Run Liu2An-Kui Yang3Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China;Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China;Department of Otorhinolaryngology Head and Neck Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510060, ChinaSun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China;<b>Objective:</b>Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC).<br/><b>Methods:</b>A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model.<br/><b>Results:</b>Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (<i>P</i><0.001). BMI was an independent prognostic factor for patients with LSCC.<br/><b>Conclusion:</b>Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC.http://www.cancerbiomed.org/index.php/cocr/article/view/893Prognosisnutritionbody mass index (BMI)laryngeal squamous cell carcinoma (LSCC)
collection DOAJ
language English
format Article
sources DOAJ
author Zhao-Qu Li
Lan Zou
Tian-Run Liu
An-Kui Yang
spellingShingle Zhao-Qu Li
Lan Zou
Tian-Run Liu
An-Kui Yang
Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
Cancer Biology & Medicine
Prognosis
nutrition
body mass index (BMI)
laryngeal squamous cell carcinoma (LSCC)
author_facet Zhao-Qu Li
Lan Zou
Tian-Run Liu
An-Kui Yang
author_sort Zhao-Qu Li
title Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_short Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_full Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_fullStr Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_full_unstemmed Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
title_sort prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
publisher China Anti-Cancer Association
series Cancer Biology & Medicine
issn 2095-3941
2095-3941
publishDate 2015-12-01
description <b>Objective:</b>Patients with head and neck cancer often suffer from malnutrition. This study aims to investigate the influence of body mass index (BMI) on the prognosis of laryngeal squamous cell carcinoma (LSCC).<br/><b>Methods:</b>A total of 473 patients with LSCC initially treated at Sun Yat-sen University Cancer Center between January 2005 and July 2009 were retrospectively reviewed. Survival analysis was performed by the Kaplan-Meier method and Cox regression model.<br/><b>Results:</b>Low BMI before treatment was significantly associated with poor overall survival in patients with LSCC (<i>P</i><0.001). BMI was an independent prognostic factor for patients with LSCC.<br/><b>Conclusion:</b>Leanness before treatment was associated with poor prognosis in patients with LSCC. Good nutritional status is favorable to improve survival in patients with LSCC.
topic Prognosis
nutrition
body mass index (BMI)
laryngeal squamous cell carcinoma (LSCC)
url http://www.cancerbiomed.org/index.php/cocr/article/view/893
work_keys_str_mv AT zhaoquli prognosticvalueofbodymassindexbeforetreatmentforlaryngealsquamouscellcarcinoma
AT lanzou prognosticvalueofbodymassindexbeforetreatmentforlaryngealsquamouscellcarcinoma
AT tianrunliu prognosticvalueofbodymassindexbeforetreatmentforlaryngealsquamouscellcarcinoma
AT ankuiyang prognosticvalueofbodymassindexbeforetreatmentforlaryngealsquamouscellcarcinoma
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