The Analysis of Genetic Polymorphism. The Relationship between Interleukin – 4 Polymorphisms and Intraepithelial Cervical Neoplasia

The Analysis of Genetic Polymorphism. The Relationship between Interleukin – 4 Polymorphisms and Intraepithelial Cervical Neoplasia

Objectives: Interleukin 4 plays a critical role in T helper 2 responses to HPV infection and angiogenesis. The present study aim to study the association between the IL4 promoter polymorphism – 590 C>T, respectively VNTR intron 2 polymorphism and cervical intraepithelial neoplasia. Material and m...

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Main Authors: Florin STAMATIAN, Gabriela CARACOSTEA, Cristina BUTUZA, Radu POPP, Daniel MUREŞAN, Sorana D. BOLBOACĂ, Ioana ROTAR, Felicia PETRIŞOR, Marius FĂRCAŞ
Format: Article
Language:English
Published: Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca 2010-09-01
Series:Applied Medical Informatics
Subjects:
Genetic polymorphism
Restriction fragment length polymorphism (RFLP)
Polymerase chain reaction (PCR)
Interleukin-4 (IL4)
Cervical intraepithelial neoplasia (CIN)
Human papiloma virus (HPV) infection
Human papiloma virus high risk (HPV-HR)
Negative for intraepithelial lesion (NILM)
Online Access:http://ami.info.umfcluj.ro/Full-text/AMI_27_2010/AMI(27)_043_052.pdf

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http://ami.info.umfcluj.ro/Full-text/AMI_27_2010/AMI(27)_043_052.pdf

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