Possible stimulatory role of CTLA-4 gene in anti-diabetic activity of ethanolic extracts of Allium sativum (Garlic) using rat model
CTLA-4 protein expressed on activated T-cells is an important mole-cule involved in T-cell homeostasis and mutations in CTLA-4 gene have been linked with autoimmune diseases such as type 1 diabetes mellitus (T1DM). T1DM is caused by selective destruction of pancreatic β-cells and its onset...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Deccan College of Medical Sciences
2019-07-01
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Series: | Journal of Medical and Allied Sciences |
Subjects: | |
Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=49716 |