Possible stimulatory role of CTLA-4 gene in anti-diabetic activity of ethanolic extracts of Allium sativum (Garlic) using rat model

CTLA-4 protein expressed on activated T-cells is an important mole-cule involved in T-cell homeostasis and mutations in CTLA-4 gene have been linked with autoimmune diseases such as type 1 diabetes mellitus (T1DM). T1DM is caused by selective destruction of pancreatic β-cells and its onset...

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Bibliographic Details
Main Authors: Dayo Rotimi Omotoso, Adeniran Oluwadamilare Akinola, Ooreoluwa Daramola
Format: Article
Language:English
Published: Deccan College of Medical Sciences 2019-07-01
Series:Journal of Medical and Allied Sciences
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=49716