miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro

miRNA-Based Rapid Differentiation of Purified Neurons from hPSCs Advancestowards Quick Screening for Neuronal Disease Phenotypes In Vitro

Obtaining differentiated cells with high physiological functions by an efficient, but simple and rapid differentiation method is crucial for modeling neuronal diseases in vitro using human pluripotent stem cells (hPSCs). Currently, methods involving the transient expression of one or a couple of tra...

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Bibliographic Details
Main Authors: Mitsuru Ishikawa, Takeshi Aoyama, Shoichiro Shibata, Takefumi Sone, Hiroyuki Miyoshi, Hirotaka Watanabe, Mari Nakamura, Saori Morota, Hiroyuki Uchino, Andrew S. Yoo, Hideyuki Okano
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
human pluripotent stem cell
excitatory neuron
neurogenin2
microrna-9/9*
microrna-124
alzheimer’s disease
presenilin1
presenilin2
Online Access:https://www.mdpi.com/2073-4409/9/3/532

Internet

https://www.mdpi.com/2073-4409/9/3/532

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