N-linked glycosylation at site 158 of the HA protein of H5N6 highly pathogenic avian influenza virus is important for viral biological properties and host immune responses

N-linked glycosylation at site 158 of the HA protein of H5N6 highly pathogenic avian influenza virus is important for viral biological properties and host immune responses

Abstract Since 2014, clade 2.3.4.4 has become the dominant epidemic branch of the Asian lineage H5 subtype highly pathogenic avian influenza virus (HPAIV) in southern and eastern China, while the H5N6 subtype is the most prevalent. We have shown earlier that lack of glycosylation at position 158 of...

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Bibliographic Details
Main Authors: Ruyi Gao, Min Gu, Liwei Shi, Kaituo Liu, Xiuli Li, Xiaoquan Wang, Jiao Hu, Xiaowen Liu, Shunlin Hu, Sujuan Chen, Daxin Peng, Xinan Jiao, Xiufan Liu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Veterinary Research
Subjects:
H5N6 avian influenza virus
glycosylation
pathogenicity
host immune response
Online Access:https://doi.org/10.1186/s13567-020-00879-6

Internet

https://doi.org/10.1186/s13567-020-00879-6

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