Ivermectin-functionalized multiwall carbon nanotube enhanced the locomotor activity and neuropathic pain by modulating M1/M2 macrophage and decrease oxidative stress in rat model of spinal cord injury

Ivermectin-functionalized multiwall carbon nanotube enhanced the locomotor activity and neuropathic pain by modulating M1/M2 macrophage and decrease oxidative stress in rat model of spinal cord injury

Since the inflammation and oxidative stress is the main pathophysiological pathway of neural damage in spinal cord injury (SCI), we tried to evaluate the role of ivermectin (IVM) combined with multi-walled carbon nanotube (MWCNT) in the treatment settings of SCI and its underlying mechanism. Wistar...

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Bibliographic Details
Main Authors: Alireza Rahbar, Saied Shakyba, Milad Ghaderi, Kiarash Kazemi, Avid Farhang Fagheh, Parsa Farsinejad, Ayda Khosravi, Parisa Afraz Louyeh, Erwin Mirzaeyian, Mohsen Chamanara, Reza Akhavan-Sigari
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Heliyon
Subjects:
Spinal cord injury
Ivermectin
Care setting
Oxidative stress
M1 macrophage
M2 macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021014146

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http://www.sciencedirect.com/science/article/pii/S2405844021014146

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