CRISPR-Cas9 System as a Versatile Tool for Genome Engineering in Human Cells

Targeted nucleases are influential instruments for intervening in genome revision with great accuracy. RNA-guided Cas9 nucleases produced from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have noticeably altered the means to modify the genomes of distinct organisms....

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Bibliographic Details
Main Authors: Xuelian Wang, Xiumin Huang, Xiuli Fang, Youzhong Zhang, Wanpeng Wang
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253117301154