Functional module detection through integration of single-cell RNA sequencing data with protein–protein interaction networks

Abstract Background Recent advances in single-cell RNA sequencing have allowed researchers to explore transcriptional function at a cellular level. In particular, single-cell RNA sequencing reveals that there exist clusters of cells with similar gene expression profiles, representing different trans...

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Bibliographic Details
Main Authors: Florian Klimm, Enrique M. Toledo, Thomas Monfeuga, Fang Zhang, Charlotte M. Deane, Gesine Reinert
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Genomics
Online Access:http://link.springer.com/article/10.1186/s12864-020-07144-2