Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state.

Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state.

To identify novel biomarkers for HIV-1 resistance, including pathways that may be critical in anti-HIV-1 vaccine design, we carried out a gene expression analysis on blood samples obtained from HIV-1 highly exposed seronegatives (HESN) from a commercial sex worker cohort in Nairobi and compared thei...

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Main Authors: Elijah M Songok, Ma Luo, Ben Liang, Paul Mclaren, Nadine Kaefer, Winnie Apidi, Genevieve Boucher, Joshua Kimani, Charles Wachihi, Rafick Sekaly, Keith Fowke, Blake T Ball, Francis A Plummer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22291902/pdf/?tool=EBI

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