PTP4A3, A Novel Target Gene of HIF-1alpha, Participates in Benzene-Induced Cell Proliferation Inhibition and Apoptosis through PI3K/AKT Pathway

PTP4A3, A Novel Target Gene of HIF-1alpha, Participates in Benzene-Induced Cell Proliferation Inhibition and Apoptosis through PI3K/AKT Pathway

Benzene, a commonly used chemical, has been confirmed to specifically affect the hematopoietic system as well as overall human health. PTP4A3 is overexpressed in leukemia cells and is related to cell proliferation. We previously found that HIF-1alpha was involved in benzene toxicity and PTP4A3 may b...

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Bibliographic Details
Main Authors: Yunqiu Pu, Fengxia Sun, Rongli Sun, Zhaodi Man, Shuangbin Ji, Kai Xu, Lihong Yin, Juan Zhang, Yuepu Pu
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Environmental Research and Public Health
Subjects:
benzene
hif-1alpha
ptp4a3
cell proliferation
apoptosis
Online Access:https://www.mdpi.com/1660-4601/17/3/910

Internet

https://www.mdpi.com/1660-4601/17/3/910

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