EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-κB signaling pathway

EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-κB signaling pathway

Abstract Accumulating evidence indicates that microglia activation is associated with an increased risk for developing Parkinson’s disease (PD). With the progressive and selective degeneration of dopaminergic (DA) neurons, proinflammatory cytokines are elevated in the substantia nigra (SN) of PD pat...

Full description

Bibliographic Details
Main Authors: Fangfang Dou, Xinkun Chu, Bei Zhang, Liang Liang, Guoqiang Lu, Jianqing Ding, Shengdi Chen
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Molecular Brain
Subjects:
Parkinson’s disease
Eriocalyxin B
Microglia-associated inflammation
DA neurons
NF-κB signaling pathways
Online Access:http://link.springer.com/article/10.1186/s13041-018-0418-z

Internet

http://link.springer.com/article/10.1186/s13041-018-0418-z

Similar Items