Endurance exercise and conjugated linoleic acid (CLA) supplementation up-regulate CYP17A1 and stimulate testosterone biosynthesis.

A new role for fat supplements, in particular conjugated linoleic acid (CLA), has been delineated in steroidogenesis, although the underlying molecular mechanisms have not yet been elucidated. The aims of the present study were to identify the pathway stimulated by CLA supplementation using a cell c...

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Bibliographic Details
Main Authors: Rosario Barone, Filippo Macaluso, Patrizia Catanese, Antonella Marino Gammazza, Luigi Rizzuto, Paola Marozzi, Giuseppe Lo Giudice, Tomaso Stampone, Francesco Cappello, Giuseppe Morici, Giovanni Zummo, Felicia Farina, Valentina Di Felice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818175?pdf=render