A quimiometria nos cursos de graduação em química: proposta do uso da análise multivariada na determinação de pkª

• Main Authors: Paulo Cesar de Souza Pereira, Camila Fabiano de Freitas, Cristiane Santi Chaves, Bianca Martins Estevão, Diogo Silva Pellosi, André Luiz Tessaro, Vagner Roberto Batistela, Ieda Spacino Scarminio, Wilker Caetano, Noboru Hioka
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Química 2014-01-01
• Series: Química Nova
• Subjects: multivariate analysis; chemometry; teaching
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014000800024&lng=en&tlng=en

An experiment was proposed applying the Chemometric approach of Multivariate Analysis for inclusion in undergraduate Chemistry courses to promote and expand the use of this analytical-statistical tool. The experiment entails the determination of the acid dissociation constant of dyes via UV-Vis electronic spectrophotometry. The dyes used show from simple equilibrium to very complex systems involving up to four protolytic species with high spectral overlap. The Chemometric methodology was more efficient than univariate methods. For use in classes, it is up to the teacher to decide which systems should be utilized given the time constraints and laboratory conditions.