Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: role of fatty acid β-oxidation and glucose

Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: role of fatty acid β-oxidation and glucose

Mitochondrial cytopathy has been associated with modifications of lipid metabolism in various situations, such as the acquisition of an abnormal adipocyte phenotype observed in multiple symmetrical lipomatosis or triglyceride (TG) accumulation in muscles associated with the myoclonic epilepsy with r...

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Bibliographic Details
Main Authors: Sébastien Vankoningsloo, Marie Piens, Christophe Lecocq, Audrey Gilson, Aurélia De Pauw, Patricia Renard, Catherine Demazy, Andrée Houbion, Martine Raes, Thierry Arnould
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Journal of Lipid Research
Subjects:
muscle carnitine palmitoyl transferase-1
phosphatidylinositol 3-kinase/Akt1/glycogen synthase kinase 3β
AMP-dependent kinase
carbohydrate-responsive element binding protein
peroxisome proliferator-activated receptor γ
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330194

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http://www.sciencedirect.com/science/article/pii/S0022227520330194

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