Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach

This work is aimed at providing a description of the complex world of drug carriers, starting from the description of this particular market in terms of revenue. Then, a brief overview of several types of conventional and innovative drug carrier systems has been included. The types of administration...

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Main Author: Paolo Trucillo
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/9/3/470
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spelling doaj-1e905a33025d4a648ddf0633cf12fbc92021-03-07T00:01:33ZengMDPI AGProcesses2227-97172021-03-01947047010.3390/pr9030470Drug Carriers: Classification, Administration, Release Profiles, and Industrial ApproachPaolo Trucillo0Department of Chemical, Material and Industrial Production Engineering (DICMAPI), University of Naples Federico II, Piazzale Vincenzo Tecchio 90, 80125 Napoli (NA), ItalyThis work is aimed at providing a description of the complex world of drug carriers, starting from the description of this particular market in terms of revenue. Then, a brief overview of several types of conventional and innovative drug carrier systems has been included. The types of administration routes were also analyzed, with a critical and qualitative comment on drug release kinetics and drug profile shapes. Carriers were classified according to their ability to provide a prolonged and targeted release. The concept of the therapeutic window has been presented, providing advantages of having pulsed drug release to avoid side effects to target tissues. A critical comment on the use of conventional and innovative techniques for the production of drug carriers by large industrial companies has been proposed. As a final attempt for this work, an overall unique schematization of a drug carrier production process has been added, highlighting the necessity to create a strong double link among world-requested versatility of drug carriers for human applications and the newly developed industrial processes.https://www.mdpi.com/2227-9717/9/3/470drug carriersdrug deliverynanoparticlesnanocapsulesliposomesniosomes
collection DOAJ
language English
format Article
sources DOAJ
author Paolo Trucillo
spellingShingle Paolo Trucillo
Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
Processes
drug carriers
drug delivery
nanoparticles
nanocapsules
liposomes
niosomes
author_facet Paolo Trucillo
author_sort Paolo Trucillo
title Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
title_short Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
title_full Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
title_fullStr Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
title_full_unstemmed Drug Carriers: Classification, Administration, Release Profiles, and Industrial Approach
title_sort drug carriers: classification, administration, release profiles, and industrial approach
publisher MDPI AG
series Processes
issn 2227-9717
publishDate 2021-03-01
description This work is aimed at providing a description of the complex world of drug carriers, starting from the description of this particular market in terms of revenue. Then, a brief overview of several types of conventional and innovative drug carrier systems has been included. The types of administration routes were also analyzed, with a critical and qualitative comment on drug release kinetics and drug profile shapes. Carriers were classified according to their ability to provide a prolonged and targeted release. The concept of the therapeutic window has been presented, providing advantages of having pulsed drug release to avoid side effects to target tissues. A critical comment on the use of conventional and innovative techniques for the production of drug carriers by large industrial companies has been proposed. As a final attempt for this work, an overall unique schematization of a drug carrier production process has been added, highlighting the necessity to create a strong double link among world-requested versatility of drug carriers for human applications and the newly developed industrial processes.
topic drug carriers
drug delivery
nanoparticles
nanocapsules
liposomes
niosomes
url https://www.mdpi.com/2227-9717/9/3/470
work_keys_str_mv AT paolotrucillo drugcarriersclassificationadministrationreleaseprofilesandindustrialapproach
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