A Comparison of the Neuroprotective Efficacy of Pharmacological Pretreatment and Antidotal Treatment in Soman-Poisoned Rats

1. To study the influence of pharmacological pretreatment (PANPAL or pyridostigmine combined with biperiden) and antidotal treatment (the oxime HI-6 plus atropine) on soman-induced neurotoxicity, male albino rats were poisoned with a lethal dose of soman (54 (g/kg i.m.; 100% of LD50 value) and obser...

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Bibliographic Details
Main Authors: Jiří Kassa, Gabriela Krejčová, Ivan Samnaliev
Format: Article
Language:English
Published: Karolinum Press 2003-01-01
Series:Acta Medica
Subjects:
Online Access:https://actamedica.lfhk.cuni.cz/46/3/0101/