Pyrrolidine dithiocarbamate and saxagliptin ameliorate ulcerative colitis in rats

Pyrrolidine dithiocarbamate and saxagliptin ameliorate ulcerative colitis in rats

Objective: To evaluate the antioxidant, immunomodulatory and anti-inflammatory activities of pyrrolidine dithiocarbamate and saxagliptin in rats with thioacetamide-induced ulcerative colitis. Methods: Animals were orally administered with a vehicle, sulfasalazine (500 mg/kg), pyrrolidine dithiocarba...

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Bibliographic Details
Main Authors: Berween Mahmoud Elmahmoudy, Mai A Abd El Fattah, Mohamed F Elyamany, Laila A Rashed
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
ulcerative colitis
inflammatory mediators
oxidative stress
pyrrolidine dithiocarbamate
saxagliptin
thioacetamide
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=9;spage=373;epage=380;aulast=Elmahmoudy

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=9;spage=373;epage=380;aulast=Elmahmoudy

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