Production of Infectious Dengue Virus in Aedes aegypti Is Dependent on the Ubiquitin Proteasome Pathway.

Dengue virus (DENV) relies on host factors to complete its life cycle in its mosquito host for subsequent transmission to humans. DENV first establishes infection in the midgut of Aedes aegypti and spreads to various mosquito organs for lifelong infection. Curiously, studies have shown that infectio...

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Bibliographic Details
Main Authors: Milly M Choy, October M Sessions, Duane J Gubler, Eng Eong Ooi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4643912?pdf=render