Aptamer Bioinformatics

Aptamer Bioinformatics

Aptamers are short nucleic acid sequences capable of specific, high-affinity molecular binding. They are isolated via SELEX (Systematic Evolution of Ligands by Exponential Enrichment), an evolutionary process that involves iterative rounds of selection and amplification before sequencing and aptamer...

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Bibliographic Details
Main Authors: Andrew B. Kinghorn, Lewis A. Fraser, Shaolin Liang, Simon Chi-Chin Shiu, Julian A. Tanner
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
aptamer
simulation
in silico selection
molecular dynamics
fragment based design
HTS
Online Access:https://www.mdpi.com/1422-0067/18/12/2516

Internet

https://www.mdpi.com/1422-0067/18/12/2516

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