Theobromine Improves Working Memory by Activating the CaMKII/CREB/BDNF Pathway in Rats

Theobromine (TB) is a primary methylxanthine found in cacao beans. cAMP-response element-binding protein (CREB) is a transcription factor, which is involved in different brain processes that bring about cellular changes in response to discrete sets of instructions, including the induction of brain-d...

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Bibliographic Details
Main Authors: Rafiad Islam, Kentaro Matsuzaki, Eri Sumiyoshi, Md Emon Hossain, Michio Hashimoto, Masanori Katakura, Naotoshi Sugimoto, Osamu Shido
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/11/4/888