A potential bat adenovirus-based oncolytic virus targeting canine cancers

Abstract Although a canine adenovirus (CAdV)-based oncolytic virus (OV) candidate targeting canine tumors has been reported, its oncolytic effect could be attenuated by CAdV vaccine-induced neutralizing antibodies in dog patients. To circumvent this issue, we focused on the bat adenovirus (BtAdV) st...

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Bibliographic Details
Main Authors: Hiromichi Matsugo, Tomoya Kitamura-Kobayashi, Haruhiko Kamiki, Hiroho Ishida, Wataru Sekine, Akiko Takenaka-Uema, Takayuki Nakagawa, Shin Murakami, Taisuke Horimoto
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96101-4