Modulation of ERQC and ERAD: A Broad-Spectrum Spanner in the Works of Cancer Cells?
Endoplasmic reticulum glycoprotein folding quality control (ERQC) and ER-associated degradation (ERAD) preside over cellular glycoprotein secretion and maintain steady glycoproteostasis. When cells turn malignant, cancer cell plasticity is affected and supported either by point mutations, preferenti...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
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Series: | Journal of Oncology |
Online Access: | http://dx.doi.org/10.1155/2019/8384913 |