An Anti-Urokinase Plasminogen Activator Receptor Antibody (ATN-658) Blocks Prostate Cancer Invasion, Migration, Growth, and Experimental Skeletal Metastasis In Vitro and In Vivo

An Anti-Urokinase Plasminogen Activator Receptor Antibody (ATN-658) Blocks Prostate Cancer Invasion, Migration, Growth, and Experimental Skeletal Metastasis In Vitro and In Vivo

Urokinase plasminogen activator receptor (uPAR) is a multidomain protein that plays important roles in the growth, invasion, and metastasis of a number of cancers. In the present study, we examined the effects of administration of a monoclonal anti-uPAR antibody (ATN-658) on prostate cancer progres...

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Bibliographic Details
Main Authors: Shafaat A. Rabbani, Bushra Ateeq, Ani Arakelian, Maria Luisa Valentino, David E. Shaw, Lisa M. Dauffenbach, Christopher A. Kerfoot, Andrew P. Mazar
Format: Article
Language:English
Published: Elsevier 2010-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558610800454

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http://www.sciencedirect.com/science/article/pii/S1476558610800454

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