Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells

Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells

ObjectiveThe mechanisms by which exposure of the late-stage progenitor cells to the anesthesia sevoflurane alters their differentiation are not known. We seek to query whether the effects of sevoflurane on late-stage progenitor cells might be regulated by apoptosis and/or autophagy.MethodsTo address...

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Bibliographic Details
Main Authors: Dongyi Tong, Zhongliang Ma, Peng Su, Shuai Wang, Ying Xu, Li Min Zhang, Ziyi Wu, Kun Liu, Ping Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
sevoflurane
dentate gyrus
apoptosis
autophagy
NF-κB
differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.590577/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2020.590577/full

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