Computer-aided molecular modeling studies of some 2, 3-dihydro-[1, 4] dioxino [2, 3-f] quinazoline derivatives as EGFRWT inhibitors

Computer-aided molecular modeling studies of some 2, 3-dihydro-[1, 4] dioxino [2, 3-f] quinazoline derivatives as EGFRWT inhibitors

Abstract Background Quinazoline are known to possess different biological activities which among is anti-cancer most especially NSCLC. Epidermal growth factor receptor (EGFR) belongs to the receptor tyrosine kinases (RTKs) family, which is known to be one of the most important therapeutic targets fo...

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Bibliographic Details
Main Authors: Muhammad Tukur Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
Format: Article
Language:English
Published: SpringerOpen 2020-04-01
Series:Beni-Suef University Journal of Basic and Applied Sciences
Subjects:
QSAR
NSCLC
EGFRWT
inhibitors
Online Access:http://link.springer.com/article/10.1186/s43088-020-00047-x

Internet

http://link.springer.com/article/10.1186/s43088-020-00047-x

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