Study of stem cell homing & self-renewal marker gene profile of ex vivo expanded human CD34+ cells manipulated with a mixture of cytokines & stromal cell-derived factor 1

Study of stem cell homing & self-renewal marker gene profile of ex vivo expanded human CD34+ cells manipulated with a mixture of cytokines & stromal cell-derived factor 1

Background & objectives: Next generation transplantation medicine aims to develop stimulating cocktail for increased ex vivo expansion of primitive hematopoietic stem and progenitor cells (HSPC). The present study was done to evaluate the cocktail GF (Thrombopoietin + Stem Cell factor + Flt3-lig...

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Bibliographic Details
Main Authors: Jyoti Kode, Navin Khattry, Ashish Bakshi, Vasanti Amrutkar, Bhausaheb Bagal, Rohini Karandikar, Pallavi Rane, Nobutaka Fujii, Shubhada Chiplunkar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Medical Research
Subjects:
Ex vivo expansion - flow cytometry - gene expression profiling - hematopoietic stem cells - homing and engraftment -stem cell self-renewal transcription factors - stromal cell- derived factor-1
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=146;issue=1;spage=56;epage=70;aulast=Kode

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=146;issue=1;spage=56;epage=70;aulast=Kode

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