Incidence of De Novo Erectile Dysfunction after Urethroplasty: A Prospective Observational Study
Purpose: De novo erectile dysfunction (ED) is a known complication after urethroplasty. Incidence and natural history of de novo ED after urethroplasty is underreported. We assessed the incidence of de novo ED after urethroplasty. Materials and Methods: Consecutive consenting urethroplasty (n=48)...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Society for Sexual Medicine and Andrology
2017-08-01
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| Series: | The World Journal of Men's Health |
| Subjects: | |
| Online Access: | https://www.wjmh.org/Synapse/Data/PDFData/2074WJMH/wjmh-35-94.pdf |
| Summary: | Purpose: De novo erectile dysfunction (ED) is a known complication after urethroplasty. Incidence and natural history of de novo
ED after urethroplasty is underreported. We assessed the incidence of de novo ED after urethroplasty.
Materials and Methods: Consecutive consenting urethroplasty (n=48) patients aged 21 to 50 years from February 2014 to July
2016 with normal preoperative erectile function as determined by an International Index of Erectile Function-5 (IIEF-5) score ≥22
were included and interviewed at 3, 6, and 12 months.
Results: In patients with anterior stricture (n=40), substitution urethroplasty (SU) was performed in 22 patients (55.0%) and
end-to-end anastomotic urethroplasty (EEAU) in 18 patients (45.0%). Their mean IIEF-5 score was 24.15±0.8 preoperatively,
20.10±4.2 at 3 months (p＜0.001), 22.70±2.3 at 6 months (p=0.0012), and 23.70±1.7 at 12 months (p=0.03), showing a recovery
of erectile function with time. All 8 patients with pelvic fracture urethral injury (PFUI) underwent progressive perineal
urethroplasty. Their mean IIEF score was 24.0±1.2 preoperatively, 18.8±5.4 at 3 months (p=0.002), 20.9±3.5 at 6 months
(p=0.37), and 22.0±1.5 at 12 months (p=0.427). The incidence of ED was similar at 1 year postoperatively between patients
with anterior stricture and PFUI and between patients who underwent EEAU or SU for anterior stricture.
Conclusions: Incidence of ED at 1 year after PFUI is similar to that after surgery for anterior stricture in patients with normal preoperative
erectile function. Among the cases of anterior stricture, recovery was better with SU at 3 months and was similar between
SU and EEAU at 1 year. |
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| ISSN: | 2287-4208 2287-4690 |