Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series

Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series

Histoplasmosis is a systemic fungal disease caused by dimorphic fungus Histoplasma capsulatum and is more common in immunocompromised patients. We report two cases of disseminated histoplasmosis in immunocompetent individuals from a non-endemic zone in Western India. Rapid diagnostic tests like urin...

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Main Authors: Arghadip Samaddar, Anuradha Sharma, Akhilesh Kumar PH, Saumya Srivastava, Twishi Shrimali, Maya Gopalakrishnan, Gopal Krishna Bohra
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Medical Mycology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211753919300600
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spelling doaj-202ed7e4e8284b2baeaaa618024e0c002020-11-25T02:05:46ZengElsevierMedical Mycology Case Reports2211-75392019-09-01254952Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case seriesArghadip Samaddar0Anuradha Sharma1Akhilesh Kumar PH2Saumya Srivastava3Twishi Shrimali4Maya Gopalakrishnan5Gopal Krishna Bohra6Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, IndiaDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, India; Corresponding author.Department of General Medicine, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, IndiaDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, IndiaDepartment of Microbiology, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, IndiaDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, IndiaDepartment of General Medicine, All India Institute of Medical Sciences, Jodhpur, 342005, Rajasthan, IndiaHistoplasmosis is a systemic fungal disease caused by dimorphic fungus Histoplasma capsulatum and is more common in immunocompromised patients. We report two cases of disseminated histoplasmosis in immunocompetent individuals from a non-endemic zone in Western India. Rapid diagnostic tests like urinary antigen detection and molecular assays comprise the need of the hour as early initiation of antifungal therapy can be life-saving. Clinicians need to be aware of this entity to prevent misdiagnosis and initiate prompt effective management.http://www.sciencedirect.com/science/article/pii/S2211753919300600
collection DOAJ
language English
format Article
sources DOAJ
author Arghadip Samaddar
Anuradha Sharma
Akhilesh Kumar PH
Saumya Srivastava
Twishi Shrimali
Maya Gopalakrishnan
Gopal Krishna Bohra
spellingShingle Arghadip Samaddar
Anuradha Sharma
Akhilesh Kumar PH
Saumya Srivastava
Twishi Shrimali
Maya Gopalakrishnan
Gopal Krishna Bohra
Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
Medical Mycology Case Reports
author_facet Arghadip Samaddar
Anuradha Sharma
Akhilesh Kumar PH
Saumya Srivastava
Twishi Shrimali
Maya Gopalakrishnan
Gopal Krishna Bohra
author_sort Arghadip Samaddar
title Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
title_short Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
title_full Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
title_fullStr Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
title_full_unstemmed Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
title_sort disseminated histoplasmosis in immunocompetent patients from an arid zone in western india: a case series
publisher Elsevier
series Medical Mycology Case Reports
issn 2211-7539
publishDate 2019-09-01
description Histoplasmosis is a systemic fungal disease caused by dimorphic fungus Histoplasma capsulatum and is more common in immunocompromised patients. We report two cases of disseminated histoplasmosis in immunocompetent individuals from a non-endemic zone in Western India. Rapid diagnostic tests like urinary antigen detection and molecular assays comprise the need of the hour as early initiation of antifungal therapy can be life-saving. Clinicians need to be aware of this entity to prevent misdiagnosis and initiate prompt effective management.
url http://www.sciencedirect.com/science/article/pii/S2211753919300600
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