Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease

Defining a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD) pathology may offer improved sensitivity to early AD compared to hippocampal volume or mesial temporal lobe alone. Since late-onset Alzheimer disease (LOAD) participants tend to have age-related co...

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Bibliographic Details
Main Authors: Aylin Dincer, Brian A. Gordon, Amrita Hari-Raj, Sarah J. Keefe, Shaney Flores, Nicole S. McKay, Angela M. Paulick, Kristine E. Shady Lewis, Rebecca L. Feldman, Russ C. Hornbeck, Ricardo Allegri, Beau M. Ances, Sarah B. Berman, Adam M. Brickman, William S. Brooks, David M. Cash, Jasmeer P. Chhatwal, Martin R. Farlow, Christian la Fougère, Nick C. Fox, Michael J. Fulham, Clifford R. Jack, Jr., Nelly Joseph-Mathurin, Celeste M. Karch, Athene Lee, Johannes Levin, Colin L. Masters, Eric M. McDade, Hwamee Oh, Richard J. Perrin, Cyrus Raji, Stephen P. Salloway, Peter R. Schofield, Yi Su, Victor L. Villemagne, Qing Wang, Michael W. Weiner, Chengjie Xiong, Igor Yakushev, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Alzheimer disease
Autosomal dominant Alzheimer disease
Preclinical
Cortical signature
Amyloid
Cortical thickness
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303284

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http://www.sciencedirect.com/science/article/pii/S2213158220303284

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