HypoxamiRs Profiling Identify miR-765 as a Regulator of the Early Stages of Vasculogenic Mimicry in SKOV3 Ovarian Cancer Cells

HypoxamiRs Profiling Identify miR-765 as a Regulator of the Early Stages of Vasculogenic Mimicry in SKOV3 Ovarian Cancer Cells

Vasculogenic mimicry (VM) is a novel cancer hallmark in which malignant cells develop matrix-associated 3D tubular networks with a lumen under hypoxia to supply nutrients needed for tumor growth. Recent studies showed that microRNAs (miRNAs) may have a role in VM regulation. In this study, we examin...

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Bibliographic Details
Main Authors: Yarely M. Salinas-Vera, Dolores Gallardo-Rincón, Raúl García-Vázquez, Olga N. Hernández-de la Cruz, Laurence A. Marchat, Juan Antonio González-Barrios, Erika Ruíz-García, Carlos Vázquez-Calzada, Estefanía Contreras-Sanzón, Martha Resendiz-Hernández, Horacio Astudillo-de la Vega, José L. Cruz-Colin, Alma D. Campos-Parra, César López-Camarillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer
vasculogenic mimicry
hypoxia
miR-765
VEGFA
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00381/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00381/full

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