Age- and α-Synuclein-Dependent Degeneration of Dopamine and Noradrenaline Neurons in the Annual Killifish Nothobranchius furzeri

Summary: Parkinson’s disease (PD) is a neurodegenerative disease characterized by α-synuclein-positive inclusion bodies and loss of neurons, including dopaminergic neurons. Difficulty in replicating PD phenotypes using animal models partly limits the understanding of PD and the therapy required. Alt...

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Bibliographic Details
Main Authors: Hideaki Matsui, Naoya Kenmochi, Kazuhiko Namikawa
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719300233