Microglia Morphological Changes in the Motor Cortex of hSOD1<sup>G93A</sup> Transgenic ALS Mice

Microglia Morphological Changes in the Motor Cortex of hSOD1<sup>G93A</sup> Transgenic ALS Mice

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of spinal motor neurons as well as corticospinal (CSN) large pyramidal neurons within cortex layer V. An intense microglia immune response has been associated with both upper and lower motor neuron degeneration in A...

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Bibliographic Details
Main Authors: Sara Migliarini, Silvia Scaricamazza, Cristiana Valle, Alberto Ferri, Massimo Pasqualetti, Elisabetta Ferraro
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Brain Sciences
Subjects:
microglia
amyotrophic lateral sclerosis
neuroimmunology
metabolic reprogramming
SOD1G93A
motor cortex
Online Access:https://www.mdpi.com/2076-3425/11/6/807

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