Interplay between Endoplasmic Reticulum Stress and Large Extracellular Vesicles (Microparticles) in Endothelial Cell Dysfunction
Upon increased demand for protein synthesis, accumulation of misfolded and/or unfolded proteins within the endoplasmic reticulum (ER), a pro-survival response is activated termed unfolded protein response (UPR), aiming at restoring the proper function of the ER. Prolonged activation of the UPR leads...
Main Authors: | Aisha Osman, Tarek Benameur, Hesham M. Korashy, Asad Zeidan, Abdelali Agouni |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/8/10/409 |
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