RNA Modifications Modulate Activation of Innate Toll-Like Receptors

Self/foreign discrimination by the innate immune system depends on receptors that identify molecular patterns as associated to pathogens. Among others, this group includes endosomal Toll-like receptors, among which Toll-like receptors (TLR) 3, 7, 8, and 13 recognize and discriminate mammalian from m...

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Bibliographic Details
Main Authors: Isabel Freund, Tatjana Eigenbrod, Mark Helm, Alexander H. Dalpke
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/2/92