A Large French Case-Control Study Emphasizes the Role of Rare Mc1R Variants in Melanoma Risk

A Large French Case-Control Study Emphasizes the Role of Rare Mc1R Variants in Melanoma Risk

Background. The MC1R gene implicated in melanogenesis and skin pigmentation is highly polymorphic. Several alleles are associated with red hair and fair skin phenotypes and contribute to melanoma risk. Objective. This work aims to assess the effect of different classes of MC1R variants, notably rare...

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Bibliographic Details
Main Authors: Hui-Han Hu, Mériem Benfodda, Nicolas Dumaz, Steven Gazal, Vincent Descamps, Agnès Bourillon, Nicole Basset-Seguin, Angélique Riffault, Khaled Ezzedine, Martine Bagot, Armand Bensussan, Philippe Saiag, Bernard Grandchamp, Nadem Soufir
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/925716

Internet

http://dx.doi.org/10.1155/2014/925716

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