Letrozole Potentiates Mitochondrial and Dendritic Spine Impairments Induced by β Amyloid

Reduced estrogens, either through aging or postsurgery breast cancer treatment with the oral nonsteroidal aromatase inhibitor letrozole, are linked with declined cognitive abilities. However, a direct link between letrozole and neuronal deficits induced by pathogenic insults associated with aging su...

Full description

Bibliographic Details
Main Authors: P. K.-Y. Chang, S. Boridy, R. A. McKinney, D. Maysinger
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.1155/2013/538979