RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative breast cancer cells

RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative breast cancer cells

Abstract Triple‐negative breast cancer (TNBC) is a malignancy that currently lacks targeted therapies. The majority of TNBCs can be characterized as basal‐like and has an expression profile enriched with genes involved in DNA damage repair and checkpoint response. Here, we report that TNBC cells are...

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Bibliographic Details
Main Authors: Jin Peng, Lichun Tang, Mengjiao Cai, Huan Chen, Jiemin Wong, Pumin Zhang
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Cancer Medicine
Subjects:
DNA damage
essential gene
genomic stability
RECQL5
triple‐negative breast cancer
Online Access:https://doi.org/10.1002/cam4.2349

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