Artemia salina as an animal model for the preliminary evaluation of snake venom-induced toxicity

Lethality and cytotoxicity assays of snake venoms and their neutralization by antivenom require many mice for the experiments. Recent developments have prompted researchers to seek alternative strategies that minimize the use of mice in line with Russel and Burch's 3Rs philosophy (Replacement,...

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Bibliographic Details
Main Authors: Mitchel Otieno Okumu, James Mucunu Mbaria, Joseph Kangangi Gikunju, Paul Gichohi Mbuthia, Vincent Odongo Madadi, Francis Okumu Ochola, Mercy Seroney Jepkorir
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Toxicon: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590171021000187