The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin
The cholesterol-dependent cytolysins (CDCs) are the archetype for the superfamily of oligomeric pore-forming proteins that includes the membrane attack complex/perforin (MACPF) family of immune defense proteins and the stonefish venom toxins (SNTX). The CDC/MACPF/SNTX family exhibits a common protei...
Main Authors: | Kristin R. Wade, Sara L. Lawrence, Allison J. Farrand, Eileen M. Hotze, Michael J. Kuiper, Michael A. Gorman, Michelle P. Christie, Santosh Panjikar, Craig J. Morton, Michael W. Parker, Rodney K. Tweten |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-04-01
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Series: | mBio |
Subjects: | |
Online Access: | https://doi.org/10.1128/mBio.00538-19 |
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