Long-Lasting Growth Hormone Regulated by the Ubiquitin-Proteasome System

Long-Lasting Growth Hormone Regulated by the Ubiquitin-Proteasome System

To increase the half-life of growth hormones, we proposed its long-lasting regulation through the ubiquitin-proteasome system (UPS). We identified lysine residues (K67, K141, and K166) that are involved in the ubiquitination of human growth hormone (hGH) using ubiquitination site prediction programs...

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Bibliographic Details
Main Authors: Myung-Sun Kim, Kyunggon Kim, Su Kyung Oh, Gidae Lee, Jin-Ock Kim, Lan Li, Jung-Hyun Park, Kwang-Hyun Baek
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
anti-ubiquitination technology
half-life
hGH
ubiquitination
Online Access:https://www.mdpi.com/1422-0067/22/12/6268

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https://www.mdpi.com/1422-0067/22/12/6268

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