3,3'-Diindolylmethane Enhances Tumor Regression After Radiation Through Protecting Normal Cells to Modulate Antitumor Immunity

3,3'-Diindolylmethane Enhances Tumor Regression After Radiation Through Protecting Normal Cells to Modulate Antitumor Immunity

Purpose: Preclinical and clinical data indicate that radiation therapy acts as an immune modifier, having both immune-stimulatory and immunosuppressive effects on the tumor-immune microenvironment (TIME). 3.3’-diindolylmethane (DIM) sensitizes tumor cells to radiation and protects mice from lethal d...

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Bibliographic Details
Main Authors: Lijun Li, MD, Renxiang Chen, PhD, Yun-Tien Lin, MS, Arslon Humayun, Albert J. Fornace, Jr., MD, Heng-Hong Li, PhD, MD
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109420303031

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http://www.sciencedirect.com/science/article/pii/S2452109420303031

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