Effect of mesenchymal stromal cell infusions on lung function in COPD patients with high CRP levels

Abstract Background We previously reported a Phase 1/2 randomized placebo-controlled trial of systemic administration of bone marrow-derived allogeneic MSCs (remestemcel-L) in COPD. While safety profile was good, no functional efficacy was observed. However, in view of growing recognition of effects...

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Bibliographic Details
Main Authors: Daniel J. Weiss, Karen Segal, Richard Casaburi, Jack Hayes, Donald Tashkin
Format: Article
Published: BMC 2021-05-01
Series:Respiratory Research
Online Access:https://doi.org/10.1186/s12931-021-01734-8