Effect of mesenchymal stromal cell infusions on lung function in COPD patients with high CRP levels

Effect of mesenchymal stromal cell infusions on lung function in COPD patients with high CRP levels

Abstract Background We previously reported a Phase 1/2 randomized placebo-controlled trial of systemic administration of bone marrow-derived allogeneic MSCs (remestemcel-L) in COPD. While safety profile was good, no functional efficacy was observed. However, in view of growing recognition of effects...

Full description

Bibliographic Details
Main Authors: Daniel J. Weiss, Karen Segal, Richard Casaburi, Jack Hayes, Donald Tashkin
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Respiratory Research
Subjects:
Mesenchymal stromal cells
Chronic obstructive pulmonary disease
Inflammation
Pulmonary function
C-reactive protein
Online Access:https://doi.org/10.1186/s12931-021-01734-8

Internet

https://doi.org/10.1186/s12931-021-01734-8

Similar Items