Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication.

Identification of a PA-binding peptide with inhibitory activity against influenza A and B virus replication.

There is an urgent need for new drugs against influenza type A and B viruses due to incomplete protection by vaccines and the emergence of resistance to current antivirals. The influenza virus polymerase complex, consisting of the PB1, PB2 and PA subunits, represents a promising target for the devel...

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Bibliographic Details
Main Authors: Kerstin Wunderlich, Daniel Mayer, Charlene Ranadheera, Anne-Sophie Holler, Benjamin Mänz, Arnold Martin, Geoffrey Chase, Werner Tegge, Ronald Frank, Ulrich Kessler, Martin Schwemmle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2759517?pdf=render

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http://europepmc.org/articles/PMC2759517?pdf=render

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