Elevated Systemic and Parasite—Antigen Stimulated Levels of Type III IFNs in a Chronic Helminth Infection and Reversal Following Anthelmintic Treatment

Elevated Systemic and Parasite—Antigen Stimulated Levels of Type III IFNs in a Chronic Helminth Infection and Reversal Following Anthelmintic Treatment

Type III IFNs are important players in immunity to viral and bacterial infections. However, their association with helminth infections has not been examined. To explore the association of Type III IFNs with Strongyloides stercoralis (Ss) infection, we examined the systemic levels of IFN lambda-1, IF...

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Bibliographic Details
Main Authors: Anuradha Rajamanickam, Saravanan Munisankar, Yukthi Bhootra, Chandrakumar Dolla, Thomas B. Nutman, Subash Babu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Type III IFNs
DC subsets
IFN lambda-1
IFN lambda-2
IFN lambda-3
Strongyloides stercoralis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02353/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02353/full

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