Synergistic Effect of Cefazolin Plus Fosfomycin Against Staphylococcus aureus in vitro and in vivo in an Experimental Galleria mellonella Model

Objectives: This study investigated the synergistic in vitro and in vivo activity of cefazolin plus fosfomycin against methicillin-susceptible and methicillin-resistant S. aureus (MSSA and MRSA) to provide the basis for a potential treatment alternative.Methods: Antimicrobial susceptibility and in v...

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Bibliographic Details
Main Authors: Manuel Kussmann, Markus Obermueller, Matthias Karer, Richard Kriz, Rui-Yang Chen, Lena Hohl, Lisa Schneider, Heinz Burgmann, Ludwig Traby, Matthias G. Vossen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.685807/full

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