A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models [version 1; referees: 2 approved]

Haematopoietic stem cell (HSC) transplantation is a critical therapy for haematopoietic malignancies and immune disorders. Incomplete or delayed engraftment of HSCs in the host results in increased risk of infection and morbidity. The mechanisms of HSC engraftment are poorly understood and understan...

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Bibliographic Details
Main Authors: Noémie Hamilton, Ian Sabroe, Stephen A. Renshaw
Format: Article
Language:English
Published: F1000 Research Ltd 2018-05-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-594/v1