A method for transplantation of human HSCs into zebrafish, to replace humanised murine transplantation models [version 1; referees: 2 approved]
Haematopoietic stem cell (HSC) transplantation is a critical therapy for haematopoietic malignancies and immune disorders. Incomplete or delayed engraftment of HSCs in the host results in increased risk of infection and morbidity. The mechanisms of HSC engraftment are poorly understood and understan...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2018-05-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-594/v1 |