Effects of Lobeglitazone, a New Thiazolidinedione, on Osteoblastogenesis and Bone Mineral Density in Mice

BackgroundBone strength is impaired in patients with type 2 diabetes mellitus despite an increase in bone mineral density (BMD). Thiazolidinedione (TZD), a peroxisome proliferator activated receptor γ agonist, promotes adipogenesis, and suppresses osteoblastogenesis. Therefore, its use is associated...

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Bibliographic Details
Main Authors: Kyoung Min Kim, Hyun-Jin Jin, Seo Yeon Lee, Hyo Jin Maeng, Gha Young Lee, Tae Jung Oh, Sung Hee Choi, Hak Chul Jang, Soo Lim
Format: Article
Language:English
Published: Academya Publishing Co. 2017-09-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-32-389.pdf